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Airline Information Great Lakes Aviation will serve Southeast Iowa Regional Airport with 2 daily flights to St. Louis, MO and 1 daily flight to Kansas City, MO where one can catch flights to the rest of the world. When using Great Lakes your flights in and out of Southeast Iowa Regional Airport connect directly to airports where our passengers can connect to nearly any airport in the world. Speaking of flying in and out of Southeast Iowa Regional Airport, passengers love the efficient terminal layout. Minutes after landing incoming passengers pick up their luggage just a dozen steps from the main terminal exit. For those flying out, the airline ticket counter is less than 50 feet from the hassle-free security check and boarding area with views of the flight line. Flight Schedule Effective October 7, 2007: Burlington to St. Louis: Flight 5080 Departs 5:44 a.m. Arrives 6:44 a.m. Operates Daily Flight 5074 Departs 3:50 p.m. Arrives 4:40 p.m. Operates Sunday-Friday St. Louis to Burlington: Flight 5073 Departs 11:10 a.m. Arrives 12:00 p.m. Operates Daily Flight 5081 Departs 8:10 p.m. Arrives 9:06 p.m. Operates Sunday-Friday Burlington to Kansas City: Flight 5073 Departs 12:10 p.m. Arrives 1:10 p.m. Operates Daily Kansas City to Burlington: Flight 5074 Departs 2:40 p.m. Arrives 3:40 p.m. Operates Sunday-Friday Flight 5081 Departs 3:00 p.m. Arrives 4:00 p.m. Operates Saturday only To purchase tickets on Great Lakes Airlines, click on the Great Lakes logo below or call the Great Lakes reservation center at 800-554-5111.
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